5th International Conference on Heart and Cardiovascular Diseases

Lidiya Komarova is a surgeon, Doctor of Medical Sciences, Professor of the Department of Surgery with a course in endoscopy at Tyumen State Medical University, Russian Federation. Winner of the All-Russian competition of university teachers "Golden Names of Higher School 2020", first-degree laureate in the "Scientist of the Year" nomination in the "Innovations" category, Grand Prix holder in the "Science and Social Responsibility" nomination of the "Academina – 2023" competition, author of more than 15 invention patents.

Objective

To investigate the effect of inferior vena cava (IVC) thrombosis on blood flow parameters using finite element modeling based on venous ultrasound data.

Materials and Methods

We employed computer modeling in the SolidWorks Flow Simulation environment, which enabled the creation of a three-dimensional reconstruction of the venous network based on clinical and instrumental data from a patient who had suffered acute iliofemoral thrombosis, and allowed for the analysis of blood flow alterations.

Results

Data analysis revealed that the relationship between the percentage of lumen stenosis and the resulting mechanical parameters is nonlinear. Of particular clinical significance is the correlation between the degree of lumen narrowing and the formation of turbulent vortices, which may determine the development of complications and underscores the necessity of an individualized approach to assessing the stress-strain state in each specific clinical case.

Conclusion

Inferior vena cava thrombosis initiates a sequential cascade of hemodynamic disturbances, ranging from local pressure elevation to the formation of turbulent blood flow, necessitating a comprehensive approach to the diagnosis and treatment of this pathological condition. When stenosis reaches 80% or more of the lumen, a transition from laminar to turbulent blood flow occurs.