Virtual Conference

Shishkin S V

Research Institute of Internal and Preventive Medicine – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Russian Federation

Title: The relationship between dietary fiber intake and the state of cognitive function in middle and old age in the population of high cardiovascular risk


Aim: The aim of the study was to investigate the relationship between dietary fiber (DF) intake and the state of cognitive function (CF) in a population sample of middle and elderly age in Novosibirsk. 

Material and Methods: The study was conducted on a random population sample from residents of Novosibirsk (n = 9360, men and women 45–69 years old), examined as a part of the international HAPIEE project. A subsample from the baseline population sample (4684 subjects) people who make up a lift from the general baseline population sample were examined for cognitive functions during the 2nd survey in 2006–2008. The examination protocol included standardized neuropsychological testing (quantitative assessment of memory function, semantic and concentration of attention) and collecting the data on nutrition (DF intake). Assessment of odds ratio (OR) was carried out using binary logistic regression by quartiles of nutrients. 

Results:  According to cross-sectional analysis, we revealed a positive association between CF indicators and DF intake in a population sample aged 45–69, while the DF intake in the groups of men and women is not statistically different. Some gender features associated with DF intake have been established: presumably, the influence of DF on semantic memory and speech activity of women is more expressed than in men. Previously identified evidence that education modifies the level of age cognitive decline in our population, apparently, is also relates to DF intake. 

Conclusions:  DF intake in men and women aged 45–69 years in a population of high cardiovascular risk is positively associated with an increase of indicators for all studied CF domains. Established relationships are instrumental in identifying risk groups of age cognitive decline.


To be updated