Haijun Zhang

Tenth People’s Hospital of Tongji University, China

Title: New ultrasound-controlled paclitaxel releasing balloon vs asymmetric drug-eluting stent in primary ST-segment elevation myocardial infarction

Abstract

Background: Application of drug-coated balloons (DCBs) is popular for the treatment of percutaneous coronary intervention (PCI). A new DCB has been designed as ultrasound-controlled paclitaxel releasing. This study was conducted to determine whether a DCB-only strategy has a similar safety profile and equal angiographic and clinical outcomes to DES implantation in primary STelevation myocardial infarction (STEMI) patients, as well as determine the efficiency and safety of this new DCB.

Methods and Results: Overall, 184 pretreated STEMI patients were randomized into DCB and DES groups with a 1:1 allocation. The main study end-point was late lumen loss (LLL) during the 9 months after PCI. Late lumen loss was reported to be 0.24±0.39mm in the DCB group and 0.31±0.38mm in the DES group (P=0.215). Diameter stenosis was 28.27±15.35% in the DCB group and 25.73±15.41% in the DES group (P=0.312). Major adverse cardiovascular events (MACEs) were reported in 3 patients (3.4%) in the DCB group and 4 patients (4.7%) in the DES group (P=0.718). TLR and TVR in the DCB group was 2.3%, 3.4% and 2.4%, 3.5% in the DES group (P=1.000), respectively. No cardiac death and stent thrombosis (ST) was found in the DCB group at 12 months clinical follow up.

Conclusions: The DCB-only strategy showed good angiographic and clinical outcomes in the 9- and 12-month follow-up periods, respectively. The VasoguardTM DCB is safe and feasible to treat STEMI patients.

Key Words: Drug-coated balloons; Drug-eluting stents; Late lumen loss; Major adverse cardiovascular events; ST-segment elevation myocardial infarction.

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WORLD CONGRESS ON HEART AND CARDIOVASCULAR DISEASES

HYBRID EVENT | MAY 18-19, 2023 | DUBAI, UAE

Haijun Zhang

Title: New ultrasound-controlled paclitaxel releasing balloon vs asymmetric drug-eluting stent in primary ST-segment elevation myocardial infarction

Abstract

Biography

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