Virtual Conference

Elena Znakharenko

Novosibirsk State Medical University, Russian Federation

Title: Clinical and molecular characteristics of non-alcoholic fatty liver disease depending on nutritional status


NAFLD and obesity, as well as the metabolic syndrome, are quite well studied, but at the same time, diagnostic and management approaches for patients with NAFLD depending on BMI remain poorly understood, which reveals the need for a clear scheme and algorithms for the treatment of NAFLD depending on the nutritional factor.We conducted a comparative clinical study involving patients with NAFLD, divided into subgroups depending on the nutritional impact on BMI (n=114 group without obesity, n=122 group with obesity), and, for comparison, conditionally healthy individuals (n=114, control group). The results of the study confirmed that studies of clinical, laboratory, experimental, nutritional and metabolic parameters make it possible to correct the diagnosis of NAFLD depending on BMI, and their sufficient diagnostic sensitivity and specificity allow the results to be included as diagnostic markers for use in routine clinical practice. Scientific research was prepared jointly with the head of the Department of Faculty Therapy named prof. G.D. Zalessky of NGMU prof. Oksana Gerasimenko.


Elena Znakharenko is a practicing dietologist, gastroenterologist for over 16 years, a member of Russian and international medical societies in dietetics and nutrition. For more than 6 years she has been a teacher at the Department of Faculty Therapy named prof. G.D. Zalessky in Novosibirsk State Medical University. At the moment, he is doing postgraduate studies at the NSMU. She is the author and co-author of more than 15 publications, including: 5 monographs, 3 study guides, Russian clinical guidelines, and scientific articles.