Introduction: Heart failure is associated with high mortality. The purpose of this study is to identify the prognostic factors in heart failure.

Methods: It was a case-control study conducted over a period of 24 months (from January 2017 to December 2018). Cases were patients hospitalized for heart failure with reduced ejection fraction who died during hospitalization and controls were patients hospitalized for heart failure reduced ejection fraction who were discharged a live.

Results: Personal history of heart failure was more represented in cases (72%) than in controls (59%) (p<0.001 and OR=3.78). The mean length of hospital stay in our study population was 10.2 ± 0.5 days. Almost all cases (92.59%) were admitted with class NYHA III and IV dyspnea (p= 0.004, OR= 2.8). The overall mean systolic blood pressure was 106.6 ± 2.1 mmHg (80 mmHg ± 4.4 in cases and 115.4 mmHg ± 1.8 in controls p=0.000 OR= 4.6). The overall mean glomerular filtration rate was 70.8 ± 2.7 ml/min (56± 4.7 ml/min in cases and 78.2 ± 3 ml/min in controls p=0.001 OR= 4.6). The mean natraemia was 134.5 ± 0.6 mmol/L (129 ± 1 mmol/L in cases and 137 ± 0.5 mmol/L in controls). Hyponatremia was strongly associated with mortality (p=0.000 OR=5.5). The mean TAPSE 15.1 ± 0.3 mm (13.9 ± 0.6 mm in cases and 15.7 ± 0.3 mm in controls p= 0.02; 2.28).

Conclusion: This study allowed us to identify factors associated with mortality in heart failure with reduced ejection fraction. We propose a predictive score to assess this mortality.

Doune Narcisse obtained his doctorate in medicine in 2012 from the University of N'Djamena in Chad. He worked as a general practitioner and chief physician at the hospital for three years before going on to specialize in cardiology in Burkina Faso for four years. After returning to Chad following his specialization, he has been working for six years as a cardiologist at the Renaissance University Hospital Center in N'Djamena, Chad. He participates in the training and supervision of medical students and cardiology residents. He has co-supervised ten doctoral theses in medicine. He is the author of some twenty scientific articles. He is one of the promoters of the General Polyclinic, which has been providing care to the population for two years.