A subclavian artery aneurysm is considered a rare occurrence in comparison to other peripheral aneurysms, making its diagnosis and management particularly important. Surgical intervention is recommended regardless of the aneurysm's size and location due to the risks associated with untreated aneurysms, including thromboembolism and rupture, which can lead to serious complications.

A 46-year-old male patient had his right subclavian artery aneurysm inadvertently discovered during a routine X-ray examination as part of his annual medical checkup. Following this diagnosis, he underwent open surgical repair through a partial sternotomy. During the procedure, the aneurysmal sac was excised, and the right subclavian artery was reconstructed with a primary end-to-end anastomosis, ensuring anatomical integrity.

While there are several reports on the surgical management of isolated right subclavian artery aneurysms, most of these cases have utilized endovascular therapy, such as intravascular repair (IVR). However, in this particular instance, the decision was made to proceed with complete aneurysm resection and primary end-to-end anastomosis. This choice was influenced by the patient's relatively young age and the identification of the aneurysm as an arteriosclerotic type, which typically presents different surgical considerations compared to other forms.

This case report highlights the successful resection of an isolated giant right subclavian artery aneurysm through a partial median sternotomy, emphasizing the importance of individualized surgical approaches based on the patient's characteristics and the specifics of the aneurysm. Such rare cases contribute valuable insights into the management of vascular conditions and the potential for favorable surgical outcomes.